Can We Make A Vaccine Against Smoking?

A vaccine for my latex allergy sounds like a terrible idea. Nothing would stop me from spending all of my money at Ikea anymore

There's a vaccine being developed in Japan for cats that retrains their body in how they produce AIM-9 proteins. In cats, the way they are normally produced causes them to get stuck in the kidneys. The vaccine basically causes them to create a recombinant version of the protein that doesn't, which is expected to effectively double the lifespan of housecats, as the fact that their kidneys get choked up with this protein is basically a ticking time bomb, and why cats die so often from kidney failure.

So, so, so, so, so, so, so glad to see you thriving after your cancer journey. You are a trooper, not only a survivor. Again, I am so glad to see you back to being you. Be well.

I recently lost my grandmother to the monster that is Alzheimer's - It's great to hear that a vaccine is being worked on that could prevent all that suffering.

God, I would LOVE a vaccine for an allergy to dogs. It's a recently developed allergy, but its so disruptive. Even with inhalers and antihistamines, I can't breathe when I visit family. (Plus I love dogs!)

Any one of these sounds like it'd be a massive boon to humanity. I'd really love that Alzheimer's one in my lifetime.

I read the thumbnail as "We've got a wax for that" and I was really confused about why they were trying to pass peanut butter off as some kind of wax.

If I had Alzheimer's, I'd want that vaccine NOW. I know it's important to test things thoroughly, but it's such a terrible disease and it's always ultimately fatal, so I'd jump on anything that offers a chance of making such a significant difference.

I got a mutated gene, apo-b, meaning that my body can’t get rid of cholesterol too well. 5 years ago I went into cardiac arrest due to a major heart attack. Those anti bodies are keeping me alive now, keeping my cholesterol levels relatively low

Would love to have my immune system stop attacking my thyroid

Hank sounds downright chipper today. I guess surviving a near death experience will do that to a person.

While the substance abuse vaccines like the anti-nicotine ones are interesting in concept, I feel like they (at least as discussed in this video) are sidestepping the core problem of what frequently causes substance abuse - things like stress and anxiety. Even if a smoker takes a nicotine vaccine they will still need to seek out something to substitute the calming effect that smoking provides, so chances are they'll just hop from one addiction to some other addiction, or otherwise switch to a different kind of problematic lifestyle - without additional therapy in parallel to the immune treatment that is.

We wanted tiny nanomachies that patrol our bodies repairing damage and eliminating threats... Turns out he had that all along but only now can program them.

I used to be dangerously allergic to bee (and wasp, hornet, etc.) stings. I went through a long process of weekly desensitization shots, and wouldn't you know it, I have not been stung since. But I have noticed that some smaller insect 'encounters' have resulted in smaller swelling than many other people get.

I've always thought it'd be cool to back up our DNA when you're healthy and if anything goes wrong later in life you have a record or whatever dna was damaged, like a big reset for whatever cells aren't doing what they're supposed to be doing, like cancers, Alzheimer's, coeliac disease, leukaemia, ms, battens disease and so on.

All of these are awesome. I'd love to just have a vaccine for my allergies instead of my 5-year extremely expensive immunotherapy. It's definitely working and I appreciate it, but it's expensive and tiresome, and the more options the better. Also sucks that my family has a genetic risk of heart disease, despite being healthy in every other way - reducing risk with a vaccine would be amazing!

My grandma had Alzheimer, I'm so scared of getting it aswell. Good that is being investigated I hope I live to see the day it's curable

I'm lowkey concerned with the hypothetical ethics of substance related vaccines. Like are parents going to be able to administer these to children when they are too young to consent and take away the ability for them to experiment later in life? Or governments forcibly vaccinating prisoners, patients, etc. A lot of people have very puritan ideas about subtances and think that experimenting with or using a drug once = substance abuse. I don't think that's the case.

"Monkeys thay were dependent on heroin" That certainly is a sentence

Thank you for covering the topic so comprehensively.