A Man Drank Throat Numbing Spray While Eating Spicy Food. This Is What Happened To His Brain.

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Published 2023-02-11
Patient RJ by Jake Rattan, Friend 1 by Matt Hernandez, Food Enjoyer by Lexi Richmond, PA/Friend 4 by Luke Menzies
Mark Rober Hot Ones:    • Mark Rober Gives Up on Science While ...  
Peer Review: Dr Araceli Morga Vera, Dr Yue Wu, Dr Katherine Johns
Spanish translation and dub: Cenzontle Voices Inc, CDMX
Portugese translation and dub: George Frederico
Music by ‪@Lifeformed‬lifeformed.bandcamp.com/

In-depth (podcast) channel ‪@HemeReview‬
Secret Channel ‪@BigEmus‬

Medicine ►    • Medicine  

There's a secret version of this video in 8k:    • A Man Drank 1 Bottle Throat Numbing S...   the music levels were out of whack on that one so I elected to publish this one instead

0:00 Throat Numbing Spray Label
0:14 A Man Swallowed 1 Bottle Throat Numbing Spray While Eating Spicy Food
2:00 haha spray go glug 😳 glug
3:29 The emergency room 🚑 where we are now
4:10 Cyanosis and oxygen saturation
5:05 Arterial blood gas vs oxygen saturation
5:58 ...but something's wrong
6:38 This brings us back to the spray...
7:16 I promise you that stuff you learned in high school chemistry was worth it because it applies here
10:07 What does the throat numbing spray have to do with this?
12:10 ONOO😞- (Biochemical breakdown)
14:49 Throat numbing spray misuse isn't new
15:52 When you misuse the antidote and it becomes a poison itself

Some images by Getty Images

These cases are patients who I, or my colleagues have seen. They are de-identified and many instances have been presented in more depth in an academic setting. These videos are not individual medical advice and are for general educational purposes only. I do not give medical advice over the internet.

References:
Benzocaine-induced Methemoglobinemia. www.ncbi.nlm.nih.gov/pmc/articles/PMC1586795/

Reported Adverse Event Cases of Methemoglobinemia Associated With Benzocaine Products. jamanetwork.com/journals/jamainternalmedicine/full…

Safety Information on Benzocaine-Containing Products. www.fda.gov/drugs/postmarket-drug-safety-informati…

Benzocaine. www.cureus.com/articles/68795-a-rare-case-of-benzo…

Continuous Methylene Blue Infusions for Treating Recurrent Methemoglobinemia. toxandhound.com/toxhound/refractory-methemoglobine…

Methemoglobinemia emcrit.org/ibcc/methemoglobinemia/

Pulse Oximetry emcrit.org/pulmcrit/pulse-oximetry/

Characterization of the methemoglobin forming metabolites of benzocaine and lidocaine. www.tandfonline.com/doi/abs/10.1080/00498254.2016.…

Identification of N-Hydroxy-para-aminobenzoic acid in a cyanotic child after benzocaine exposure. pubmed.ncbi.nlm.nih.gov/25211007/

A mitochondrial superoxide theory for oxidative stress diseases and aging. www.ncbi.nlm.nih.gov/pmc/articles/PMC4306659/

4.2 Oxygen Binding: chem.libretexts.org/Bookshelves/General_Chemistry/…

Benzocaine Label without Methemoglobinemia warning: fda.report/DailyMed/29890aa7-915a-46db-943d-a041d4…

Acute Phenol Poisoning: www.jstor.org/stable/27720955

Goldfrank's Toxicologic Emergencies 11th Edition Text

Methemoglobinemia. UpToDate. Accessed 01 Feb 20

All Comments (21)
  • @PowerSynopsis
    This channel has taught me that people will ingest literally anything
  • Shoutout to RJ's friends for realizing what was happening and taking the appropriate steps.
  • @TK.000
    His friends saved his life. I'm glad they were aware, some people are oblivious to their surroundings.
  • I am incredibly amazed that the doctors picked up on what was happening with the chemical reactions. To learn those specifics, then remember them, then remember them in an applicable situation is very impressive.
  • @ShihammeDarc
    He may have made a full recovery physically, but his friends will never let him forget what he did.
  • @noel0020
    The stories featured on this channel range from "oh my god, what an extreme outcome to something so mundane, this could happen to anyone" to "why on earth would someone drink a snow globe"
  • @catbert7
    Props to that friend who had the base intellect to read the bottle. 6:23: This is where it got really scary. Really love that you explained the electron interactions.
  • @yatta747
    I love how he says "And be well" and makes it sound like a threat
  • @sjc4
    props to the patient's friends for reading the label carefully and taking appropriate and swift action. probably saved his life
  • @niceboi6364
    Is anyone going to talk about how dedicated this young doctor is? I mean. Dubbing his videos on Spanish and Portuguese just so more people can access to this kind of content isn't something your average YouTube is willing to do. Congrats on your expansion efforts, Chubbyemu!
  • @cryofpaine
    Apparently the way to deal with spicy foods is frozen key lime pie. The cold helps soothe. The fat coats your tongue, and the capsaicin is fat soluble. The acid from the lime juice breaks down the capsaicin. And the strong sugar flavor competes with the signals from the pain receptors in your tongue to drown it out. Also, holding your nose when you eat helps dull the sensation some too.
  • @coolstorybro1775
    A while ago when I was in the hospital I (briefly) had to have an NG tube placed and it really irritated my throat so they gave me the same kind of throat spray. It didnt really work so I kept asking for more but they had a very strict schedule of how often i could have it, and they wouldn't leave it in my room, I had to ask the nurse for it each time. I got fed up and asked my dad to go down to the pharmacy/convenience store and just buy some for me, but they didnt have any. So thank you to Johns Hopkins for being so "mean" to me because I totally would have been dumb enough the down the bottle
  • @Myllz
    "One of the roommates dropped out quick because they didn't like spicy foods, they just wanted to taste flavor and enjoy what they ate." - The smart friend.
  • @jonatgan8546
    i love when the consequences seem completely hyperbolic compared to the cause. like “a man stubbed his toe on a grand piano. this is how his entire nervous system shut down.”
  • @supravlieg
    Any video related to medical procedures in the USA should mention the hospital bill at the end.
  • @isaiahslabach7494
    This guy amazes me. Literally Everything he says he explains in thorough detail. This guy will teach you so much
  • @Alyrulz421
    The unusual thing in this case isn’t the irresponsible use or consumption of medicine/food/nonfood, it’s the quick and measured response from RJs friends. It’s always sad hearing the stories where they would’ve been fine if immediately treated but no one figured out they needed help until much later. Bravo to them!
  • “As they drive him to the emergency room” what good friends knowing an RJ didn’t need an ambulance with a 5k bill on top of the 20k hospital bill 😊
  • @arti9766
    You're honestly such a great storyteller. I've been binge watching your videos for the past days and even though I have no idea what you're talking about some times, the effort that is put in these videos is immaculate. Keep up the good work!