Interstitial lung disease, Causes, Signs and Symptoms, Diagnosis and Treatment

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Published 2021-01-31
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Chapters

0:00 Introduction
1:18 Causes of Interstitial lung disease
3:13 Symptoms and Diagnosis of Interstitial lung disease
3:53 Treatment of Interstitial lung disease.



Interstitial lung disease (ILD), or diffuse parenchymal lung disease (DPLD),[3] is a group of respiratory diseases affecting the interstitium (the tissue and space around the alveoli (air sacs) of the lungs.[4] It concerns alveolar epithelium, pulmonary capillary endothelium, basement membrane, and perivascular and perilymphatic tissues. It may occur when an injury to the lungs triggers an abnormal healing response. Ordinarily, the body generates just the right amount of tissue to repair damage, but in interstitial lung disease, the repair process is disrupted, and the tissue around the air sacs (alveoli) becomes scarred and thickened. This makes it more difficult for oxygen to pass into the bloodstream. The disease presents itself with the following symptoms: shortness of breath, nonproductive coughing, fatigue, and weight loss, which tend to develop slowly, over several months. The average rate of survival for someone with this disease is between three and five years.[5] The term ILD is used to distinguish these diseases from obstructive airways diseases.

There are specific types in children, known as children's interstitial lung diseases. The acronym ChILD is sometimes used for this group of diseases.[6]

Prolonged ILD may result in pulmonary fibrosis, but this is not always the case. Idiopathic pulmonary fibrosis is interstitial lung disease for which no obvious cause can be identified (idiopathic) and is associated with typical findings both radiographic (basal and pleural-based fibrosis with honeycombing) and pathologic (temporally and spatially heterogeneous fibrosis, histopathologic honeycombing, and fibroblastic foci).

All Comments (8)
  • Much needed video with everything to know. From a lazy Nurse.
  • @tshady32
    This person said in 2013 that 78% people died that had this
  • @mynatti3209
    Is there any hope for me to survive & go back to work as a surgical technologist? I’m only 32 they don’t know what I have they only said I had Pneumonia I don’t smoke anything nor do I have and family history of lung disease I need help if anybody can please