A Grape Made of... Meat?? - Tissue Recellularization
9,850,674
Published 2019-10-29
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Decellularization is a pretty strange process. Using a special type of soap, it's possible to remove all the cellular material from a piece of tissue, leaving only the connective proteins and polymers behind that normally hold the cells in place. It leaves you with something that looks like the starting material, but is really just an empty sponge called a scaffold.
Doctors and scientists have been exploring this technique for many years because those empty scaffolds are extremely useful for cell culture. By seeding them with cells taken from a patient, it's possible to grow a brand new organ or tissue able to be transplanted into a patient, potentially saving their life. The same technique could even be used to make lab grown meat.
Today we explore this amazing process and turn an ordinary grape, into meat.
More reading:
Review paper - onlinelibrary.wiley.com/doi/pdf/10.1111/tri.13462?…
Andrew Pelling papers - journals.plos.org/plosone/article?id=10.1371/journ…
pubs.acs.org/doi/abs/10.1021/acsbiomaterials.8b001…
Gabriels stuff:
www.scihouse.space/
www.instagram.com/glimsd/
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All Comments (21)
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I like how this seems to have two applications: 1. Organ transplants 2. mmmm meat berry
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"Nice ear" "Thanks, they're from Apple"
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the idea that lab-grown organs can exist within my lifetime is insane. it's something my family has been hoping for since my brother got his kidney transplant
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I like how he asks, "Why don't we make a meat berry?" with the candour of asking, "Why don't we get some Macdonald's icecream?"
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the fact this kind/quality of content is completely free on yt is insane to me. mad props to the educational section of yt.
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2018: they did surgery on a grape 2019: they did surgery with a grape
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I remember my friend said that he could turn a grape into an onion, he just peeled the skin of and I believed it was an onion.
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The full video you made three years ago was actually what inspired me to study biology! And this semester I'm going to write my bachelor thesis :) thanks for that, you are awesome!
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I came here for meat berries and I came out actually educated on cells growing and organs and I feel smart
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It's amazing that I read a scifi comic that's at least 20 years old by now where they had this exact concept of decelluarising an entire human and fill him back up with new cells to extend their lifespan to several centuries.
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Given your title this is NOT what I was expecting. You’re a fantastic speaker, and this script, it’s at a peak of greatness. I love this. I learned something today. Thanks a lot man.
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Doctor: Congratulations we found a heart to replace yours! Patient: Oh, well who's the donor? Doctor: Grape
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2018: They did surgery on a grape 2019: They did cell replacement therapy on a grape 2020: We have become the grape
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Embedding tissues in paraffin could enhance the quality of the slices for microscopic visualization. I'm very interested in seeing comparative images of grape tissue, hollow grape cellulose, and meat berry tissue prepared using this method. The results must be fascinating. Although I found a video on this topic informative, I'd appreciate more detailed visual comparisons.
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From "they did surgery on a grape" to "the made a meat grape". Amazing
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2025: The grape did surgery on me
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The chemical “gently” disintegrates every single one of the cells.
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1:03 Ah crap.. I forgot to water my liver…
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Patient: lost a testicle Doctor: puts a grape instead
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So Groot is basically a decellularized human with plant cells.
