The Evidence For Why Viral Persistence Might be Causing Long Covid | With Dr Amy Proal

thank you. this is the science behind my last 2 years. your advocacy and platform are truly appreciated. it always helps me feel a little less crazy and a lot more informed

Excellent. Please have a follow up with Dr Amy Proal. This is Amazing information. The corporations that made trillions during COVID need to step up and support this Research.

Just wanna say to everyone stay strong we will be better one day, there’s a lot of research going on and also there’s a lot of profit in potential treatments, we will find answers. Do not give up, you are not alone although it really can feel that way. We will all have an outlook on life we might never have had before being forced into such a bad situation. We will get through this. Also thank you to Gez for your content it really gives us a lot of hope for the future and makes us feel like we are not alone.

Insanely good information! The stuff about the vagus nerve has connected so many dots for my symptoms especially. Fascinating!!

For those suffering long covid issues, look into Wim Hof Method (cold showers/baths & breathing techniques). Not for all, but I'm telling you, it has absolutely had a tremendously positive affect on the symptoms I was experiencing - primarily extreme fatigue, brain fog, periodic nervous issues. I'm typically a very physically active male (60-year old), and had issues just doing one basic set of push-ups. That was the case as recent as 9 weeks ago. I've been taking cold showers daily since then (as well as one round of the controlled breathing to get my day started-3 sets of 30 breaths & holds), and have progressively returned to "normal". 30-minute/4 days per week hard core weight workouts are no longer an issue, though I don't pack as much in as I used to, and I'm not up to my normal 45-minute strength training regimen. Still, a far cry from not being able to do more than 1 set of basic pushups. I noticed MASSIVE improvements, especially during the first 3-4 weeks. Ease into the cold showers if it's tough for you start. Take your 'normal' shower and end it with cold for say 30 seconds. Gradually increase the time under cold water each day until you're taking full-on cold showers. My wife (also a long covid sufferer, though not as bad as mine), calls it the fountain of youth. Research has shown that the cold effect on the body has tremendous positive effects on one's circulatory and immune systems, while the breathing has more positive effects pertaining to the nervous system. Wondering if this isn't somehow the reason for all of my personal improvement? Anyway, look into this stuff (Wim Hof/Wim Hof Method) if you're frustrated and looking for potential aid in your long covid symptoms. It's certainly helped with mine! And Gez, thanks so much for this channel! Like another commented below, you deserve an award for all the time you've devoted to researching this topic!

I find the vagus nerve discussion so interesting, because my very first symptom was dizziness that is so unnatural for me.

Thank you again Gez and thank you to Dr. Amy.Brilliant video!

I am one of the long haulers here. It's a frustrating situation. Very informative video, very educational, and very clear information. Thanks👍

Dr Proal, you are so wonderful - words can’t express my gratitude for all you do for us… so informative… Gez, absolutely fascinating indeed… again, thank-you…

Adding to the idea of gut persistence: I learned just recently in Phillipp Detmer's new book "Immune" that the immune system of the gut is quite different than the immune system of the rest of the body. Prime example is that the gut immune system does not trigger the inflammation response like the body immune system does because the gut immune system is constantly attacking things in the gut. If it were triggering inflam at every time it attacked something, then our guts would be constantly inflamed.

Thank you so much for this!!! I came across your channel just before I caught covid and was sharing your video about how to avoid long covid to everyone I knew as we are currently in a surge where I live. I have autoimmune arthritis and fibromyalgia - there is some new research from last year that suggests fibromyalgia is indeed an autoimmune disease, which makes a whole lot of sense, but also it has been known for a long time that autoimmune disease is highly correlated / linked with history of bacterial or viral infections. I had frequent, recurring throat infections as a teenager and then went on to develop autoimmune arthritis around age 24, and was diagnosed just last year also with fibromyalgia too although I probably have had it for a year or two before that. I recently recovered from a mild infection of covid, and have a number things in my mind, especially after watching this video! 1: a couple of the common forms of long covid is fatigue and joint/muscle pain… how will I be able to tell the difference between fibromyalgia and those long covid symptoms ?? 2: after I got better…. My throat has began to get sore again even though I’m testing negative. Is this re-activation of the infection I used to get as a teen I will feel very 😵‍💫 but as a teen I never saw a doctor for it even though it lasted years, I never learnt exactly what was causing it! now I’m an adult and have a good and frequent relationship with my doctor so maybe can get on top of it…. 3: this video made me wonder if potentially some autoimmune diseases and conditions like fibromyalgia and MECFS, MCAS might be able to be treated and even cured through anti virals in the future if they are caused by viruses hiding sneakily in the body and continuing to set us off…. A future where I no longer need a handful of meds every day and doses of immune suppressants to stay well is very exciting one I hope to live long enough to see. As for those struggling with long covid fatigue and neuropathic pain - I have my fingers crossed that treatments, even if they are only symptom masking ones rather than actually treating the cause of the disease, become studied and available to you soon. I have found amitriptyline life changing for my fibromyalgia and do wonder if it might be something that could help long haulers until better science and medicines become available. Stay strong spoonies 🥄 hopefully some huge research that will change many of our lives is on the horizon!

18:01 - mention of findings from “ACE2-independent infection of T lymphocytes by SARS-CoV-2”. 18:35 - multiple redundant proteins to that degrade host interferon pathways. Lots of papers about this but very little public discussion. 20:45 - super important point about the reality of anatomical sanctuaries. 27:10 - the unlikelihood of “it’s just debris” given how ubiquitous RNAses are. A lot of points that aren’t mentioned often.

Thank you Amy and Gez. Amy is one of my greatest hopes

Another fantastic film. Certainly another piece of the puzzle. Thanks Gez

Thanks so much for this, Gez & Amy. Very much looking forward to more progress on the antiviral front.

Going to listen to this again. Your guests are so interesting and it's exciting to learn how everything may tie together. Thanks Gez!

Amazing stuff Gez. Thanks again for all you do!

A+ (again). Both fascinating and frightening at the same time. When will we finally crack this, I wonder.

Brilliant, I appreciate the way Amy looks at how the various pieces in the puzzle might fit together - all sounds very plausible.

I have been researching this subject for 4+ years; regarding ME/CFS. I found small fiber poly neuropathy to be a core symptom, caused by micro clotting. This creates Dysautonomia. Hyperbaric oxygen treatments early would do much to prevent long term suffering and damage. Thank you for bringing in the experts that you do!!!